Study of Ecological Relationship of Yeast Species with Candida albicans in the Context of Vulvovaginal Infections

The role of the fungal community, mycobiota, in health vagina is currently an important area research. emergence new sequencing technologies and advances bioinformatics made possible discovery novel fungi inhabiting this niche. Candida spp. constitutes most group opportunistic pathogenic fungi, being prevalent species vulvovaginal infections. However, such as Rhodotorula spp., Naganishia Malassezia have emerged potential pathogens niche, therefore it clinically relevant to understand their ecological interaction with main aim study was evaluate impact yeasts on albicans’ pathogenicity, focusing in-vitro growth, biofilm formation at different times co-culture germ tube formation. assays were performed isolated or co-cultures C. albicans (ATCC10231) one other yeast species: mucilaginosa (DSM13621), furfur (DSM6170) albida (DSM70215). results showed that M. creates a symbiotic relationship albicans, enhancing growth rate (149.69%), (119.8%) inducing higher amount biomass co-culture, both when mixed (154.1%) preformed (166.8%). As for R. N. albida, antagonistic (with significant decrease all assays), thus possibly repressing mixture’s pathogenicity. These shed light complex interactions between vaginal mycobiome.